Spoiler Warning:Plot and/or ending details are in the text which follows.
Time to get personal. We gonna strike at the heart of the Latino operation - I'm gonna blow their precious Copacabana Club and every motherfucker in it to next week. I need you to cover my ass.
The second task that Ray does for Isaiah is blow up the Copacabana Club, the main headquarters of the Latinos, as payback for allegedly stealing his bonds, even though Ray and Slink were the ones who took Isaiah's bonds to hire the Thompsons to steal coke from the Latinos and sell them to Zhou before they betrayed the duo.
Ray follows Isaiah in his car to the Copacabana Club in Harlem, where its owner, Romero, has previously banned Ray and Slink from entering. Ray plants the bomb near the club's entrance, luring all of the Latinos outside, and finishing them off. Ray and Isaiah drive away from the club, but are forced to split up once more Latino reinforcements show up in Cerranos. Ray kills the Latinos and beats Isaiah to the rendezvous point in the Bronx.
Once the player kills all of the Latinos outside the club and starts following Isaiah's car, they'll be attacked by more Latinos in their Cerranos. The player needs to focus on killing the Latinos in their cars instead of following Isaiah.
Time to get personal. We gonna strike at the heart of the Latino operation - I'm gonna blow their precious Copacabana Club and every motherfucker in it to next week. I need you to cover my ass.
So here's what we gotta do - we plant this bomb at the club, then get the hell out before anybody's the wiser. Anybody follows us, it'll be your job to deal with them. Drag them off my ass, so to speak.
Ray follows Isaiah to the Copacabana Club in Harlem.
Isaiah gets back into his car and drives away. Ray gets into a nearby Cerrano and follows Isaiah, until they get chased by more Latinos in their Cerranos.